Pharmaceutical products distributor McKesson will open a new regional distribution center in Moore, OK, according to a June 24 announcement from the Oklahoma Department of Commerce.

The 330,000-square-foot facility will be located at North Moore Industrial Park and is expected to replace an existing distribution center while expanding McKesson’s capacity and modernizing its capabilities. The site will serve as a regional pharmaceutical distribution hub, supporting the movement of pharmaceuticals and medical products across a multi-state region.

The Oklahoma Department of Commerce said the project represents a $179 million capital investment and will create more than 200 direct jobs. An economic impact analysis from the Cleveland County Economic Development Coalition projected 633 total jobs — including direct, indirect and induced impacts — by 2029, the first full year of operations, and annually thereafter.

The facility is expected to include digitally enabled logistics, automation, precision inventory management, expanded cold chain capacity and 100% standby power to support operations during adverse conditions. McKesson said the investment will strengthen its ability to serve customers in Oklahoma, Texas and the surrounding region.

“The healthcare supply chain grows more complex, from supporting advanced therapies with specialized handling and storage to navigating modernization, security, and supply constraints,” said Gene Cavacini, President of U.S. Pharmaceutical Distribution at McKesson. “Patients are counting on consistent, reliable access to critical therapies.”

Cavacini added that the investment “strengthens our ability to deliver with speed, precision and resilience, while expanding capacity to better serve Oklahoma, Texas and the surrounding region.”

With $359 billion in 2025 revenue, McKesson was No. 1 on MDM’s 2026 Top Distributors List for Pharmaceuticals/Healthcare. McKesson distributes approximately one-third of all pharmaceuticals in North America and operates a digitally connected distribution network serving pharmacies, hospitals and other healthcare providers, according to the announcement. The Oklahoma Department of Commerce said McKesson selected Moore after evaluating competing markets across the central United States.